Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/16/54bd3b05b3644c554e5cb7c9db65d4/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4c/eca24af5aebcf332713d1e1f23ea46/V4_0001_RNA_0005_23H5VFLT4_s13.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/16/54bd3b05b3644c554e5cb7c9db65d4/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5b456d70-fab3-4fcc-916c-bc437f411fba/48/d36e0303d259ad82d7d96e756f6134/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 5 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 84
Pass (FILTER=PASS): 15 (17.9%)
Fail (FILTER=FAIL): 69 (82.1%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 5
All 5 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 19
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 14
confidence_below_min(medium<high): 6
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 3
confidence_below_min(low<high): 3
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
confidence_below_min(medium<high);aih_curated_blacklist: 2
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 2
total_reads_below_min(7.0<8.0);aih_curated_blacklist: 1
total_reads_below_min(6.0<8.0): 1
total_reads_below_min(3.0<8.0): 1
total_reads_below_min(3.0<8.0);aih_curated_blacklist: 1
Breakdown by confidence:
high: 15 pass, 4 fail (total: 19)
low: 0 pass, 53 fail (total: 53)
medium: 0 pass, 12 fail (total: 12)
Arriba filter: 84 rows -> 15 PASS; wrote V4_0001_RNA_0005_23H5VFLT4_s13.arriba.fusions.filtered.tsv and V4_0001_RNA_0005_23H5VFLT4_s13.arriba.fusions.filtered_pass_only.tsv
Summary written to: V4_0001_RNA_0005_23H5VFLT4_s13.arriba.fusions.filter_summary.txt