Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/be/a01ca62e20d51cab2113cd85507649/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/be/a01ca62e20d51cab2113cd85507649/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d5/6e9dca03057594f2d215bb0039e9b1/V4_0001_RNA_0005_23H5VFLT4_s42.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5b456d70-fab3-4fcc-916c-bc437f411fba/48/d36e0303d259ad82d7d96e756f6134/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 7 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 86
Pass (FILTER=PASS): 18 (20.9%)
Fail (FILTER=FAIL): 68 (79.1%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 7
All 7 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 17
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 13
confidence_below_min(medium<high): 6
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 5
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(low<high): 2
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 2
aih_curated_blacklist: 2
total_reads_below_min(4.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(6.0<8.0);aih_curated_blacklist: 1
total_reads_below_min(6.0<8.0);aih_curated_blacklist: 1
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 1
Breakdown by confidence:
high: 18 pass, 5 fail (total: 23)
low: 0 pass, 53 fail (total: 53)
medium: 0 pass, 10 fail (total: 10)
Arriba filter: 86 rows -> 18 PASS; wrote V4_0001_RNA_0005_23H5VFLT4_s42.arriba.fusions.filtered.tsv and V4_0001_RNA_0005_23H5VFLT4_s42.arriba.fusions.filtered_pass_only.tsv
Summary written to: V4_0001_RNA_0005_23H5VFLT4_s42.arriba.fusions.filter_summary.txt