Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c8/af5cf279a32cc6578cc8c8645f8b1d/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c8/af5cf279a32cc6578cc8c8645f8b1d/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/92/d5ac402051566ee9af4a1bcbd2fa76/tih_rna_sample_00218_23H5VFLT4_s10.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5b456d70-fab3-4fcc-916c-bc437f411fba/48/d36e0303d259ad82d7d96e756f6134/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 8 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 360
  Pass (FILTER=PASS): 54 (15.0%)
  Fail (FILTER=FAIL): 306 (85.0%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 8
  All 8 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 72
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 36
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 33
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 31
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 24
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 24
  confidence_below_min(low<high): 15
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 13
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 10
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 9
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 8
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
  confidence_below_min(medium<high);aih_curated_blacklist: 4
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 4
  confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 3

Breakdown by confidence:
  high: 54 pass, 9 fail (total: 63)
  low: 0 pass, 133 fail (total: 133)
  medium: 0 pass, 164 fail (total: 164)
Arriba filter: 360 rows -> 54 PASS; wrote tih_rna_sample_00218_23H5VFLT4_s10.arriba.fusions.filtered.tsv and tih_rna_sample_00218_23H5VFLT4_s10.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00218_23H5VFLT4_s10.arriba.fusions.filter_summary.txt