Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c1/b41e0c0189bb72d8073e109ce76111/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c1/b41e0c0189bb72d8073e109ce76111/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/bd/f74833b7ad9d64f68fd2ce5c5f0822/V4_0001_RNA_0005_23H5VFLT4_s12.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5b456d70-fab3-4fcc-916c-bc437f411fba/48/d36e0303d259ad82d7d96e756f6134/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 6 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 97
Pass (FILTER=PASS): 16 (16.5%)
Fail (FILTER=FAIL): 81 (83.5%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 6
All 6 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 21
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 14
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 6
confidence_below_min(medium<high): 5
confidence_below_min(low<high): 4
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 3
confidence_below_min(medium<high);aih_curated_blacklist: 3
aih_curated_blacklist: 2
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 2
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(2.0<8.0);aih_curated_blacklist: 1
Breakdown by confidence:
high: 16 pass, 2 fail (total: 18)
low: 0 pass, 68 fail (total: 68)
medium: 0 pass, 11 fail (total: 11)
Arriba filter: 97 rows -> 16 PASS; wrote V4_0001_RNA_0005_23H5VFLT4_s12.arriba.fusions.filtered.tsv and V4_0001_RNA_0005_23H5VFLT4_s12.arriba.fusions.filtered_pass_only.tsv
Summary written to: V4_0001_RNA_0005_23H5VFLT4_s12.arriba.fusions.filter_summary.txt