Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/98/5699f04136a7c717fdbba93b21a24f/V4_0001_RNA_0005_23H5VFLT4_s11.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/34/8fc9f3a503ed5f36b98d5e93ee2a35/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/34/8fc9f3a503ed5f36b98d5e93ee2a35/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5b456d70-fab3-4fcc-916c-bc437f411fba/48/d36e0303d259ad82d7d96e756f6134/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 10 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 108
Pass (FILTER=PASS): 18 (16.7%)
Fail (FILTER=FAIL): 90 (83.3%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 10
All 10 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 18
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 14
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 8
confidence_below_min(medium<high): 7
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 7
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 5
confidence_below_min(low<high): 4
confidence_below_min(medium<high);aih_curated_blacklist: 4
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 1
aih_curated_blacklist: 1
total_reads_below_min(6.0<8.0);aih_curated_blacklist: 1
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 1
Breakdown by confidence:
high: 18 pass, 4 fail (total: 22)
low: 0 pass, 65 fail (total: 65)
medium: 0 pass, 21 fail (total: 21)
Arriba filter: 108 rows -> 18 PASS; wrote V4_0001_RNA_0005_23H5VFLT4_s11.arriba.fusions.filtered.tsv and V4_0001_RNA_0005_23H5VFLT4_s11.arriba.fusions.filtered_pass_only.tsv
Summary written to: V4_0001_RNA_0005_23H5VFLT4_s11.arriba.fusions.filter_summary.txt