Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/af/50926a74aa1376e74d4f4985bf1eb8/V4_0001_RNA_0005_23H5VFLT4_s39.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f6/617c1f253a476f07e4db5b7678a403/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f6/617c1f253a476f07e4db5b7678a403/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5b456d70-fab3-4fcc-916c-bc437f411fba/48/d36e0303d259ad82d7d96e756f6134/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 4 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 54
  Pass (FILTER=PASS): 4 (7.4%)
  Fail (FILTER=FAIL): 50 (92.6%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 4
  All 4 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 13
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 4
  confidence_below_min(medium<high);aih_curated_blacklist: 3
  confidence_below_min(medium<high): 3
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 3
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 3
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 3
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 3
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 3
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 3
  confidence_below_min(low<high): 2
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 2
  total_reads_below_min(6.0<8.0): 1
  total_reads_below_min(4.0<8.0): 1
  confidence_below_min(medium<high);total_reads_below_min(7.0<8.0);aih_curated_blacklist: 1

Breakdown by confidence:
  high: 4 pass, 2 fail (total: 6)
  low: 0 pass, 31 fail (total: 31)
  medium: 0 pass, 17 fail (total: 17)
Arriba filter: 54 rows -> 4 PASS; wrote V4_0001_RNA_0005_23H5VFLT4_s39.arriba.fusions.filtered.tsv and V4_0001_RNA_0005_23H5VFLT4_s39.arriba.fusions.filtered_pass_only.tsv
Summary written to: V4_0001_RNA_0005_23H5VFLT4_s39.arriba.fusions.filter_summary.txt