File Info

Filename
.command.err
Full Path
s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/e3/769f8aa83b47436208d94ea1f27306/.command.err
Size
30.6 KB
Attempt
Done.
-parsing GTF file: /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39.gtf
* Running CMD: /usr/local/bin/STAR  --runThreadN 8  --genomeDir /tmp/nxf.0HSd2SUmKP/ctat_genome_lib_build_dir/ref_genome.fa.star.idx  --outSAMtype BAM SortedByCoordinate  --twopassMode None  --alignSJDBoverhangMin 10  --genomeSuffixLengthMax 10000 --limitBAMsortRAM 47271261705  --alignInsertionFlush Right   --alignMatesGapMax 100000  --alignIntronMax 100000  --outSAMattributes All  --readFilesIn /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39_1.fastp.fastq.gz /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39_2.fastp.fastq.gz  --genomeFastaFiles /tmp/nxf.0HSd2SUmKP/fi_workdir/tih_rna_sample_00089_23H5VFLT4_s39.fa  --outSAMfilter KeepAllAddedReferences  --sjdbGTFfile /tmp/nxf.0HSd2SUmKP/fi_workdir/tih_rna_sample_00089_23H5VFLT4_s39.gtf  --alignSJstitchMismatchNmax 5 -1 5 5  --scoreGapNoncan -6  --readFilesCommand 'gunzip -c' 
* Running CMD: mv Aligned.sortedByCoord.out.bam tih_rna_sample_00089_23H5VFLT4_s39.star.sortedByCoord.out.bam
* Running CMD: samtools index tih_rna_sample_00089_23H5VFLT4_s39.star.sortedByCoord.out.bam
11:05:26 : INFO : Done.
-parsing GTF file: /tmp/nxf.0HSd2SUmKP/fi_workdir/tih_rna_sample_00089_23H5VFLT4_s39.gtf
-parsing /tmp/nxf.0HSd2SUmKP/fi_workdir/tih_rna_sample_00089_23H5VFLT4_s39.star.cSorted.dupsMarked.bam

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[1930000]   -done parsing /tmp/nxf.0HSd2SUmKP/fi_workdir/tih_rna_sample_00089_23H5VFLT4_s39.star.cSorted.dupsMarked.bam.  Extracting junction info.
junction read elimination tally: $VAR1 = {
          'excessive soft clipping' => 13184,
          'small anchor length' => 49,
          'low complexity anchor region' => 16,
          'num genes matched < 2' => 11,
          'exons hit < 2' => 5,
          'num_hits: 2 != num_counted_on_fusion_contigs 1 ' => 1030,
          'num_hits: 6 != num_counted_on_fusion_contigs 4 ' => 12,
          'per_id < 96' => 7457,
          'num_hits: 3 != num_counted_on_fusion_contigs 1 ' => 11,
          'num_hits: 6 != num_counted_on_fusion_contigs 3 ' => 33,
          'num_hits: 4 != num_counted_on_fusion_contigs 3 ' => 18,
          'num_hits: 4 != num_counted_on_fusion_contigs 2 ' => 36,
          ' ** passed ** ' => 5730,
          'num_hits: 3 != num_counted_on_fusion_contigs 2 ' => 16
        };
-writing fusion junction support info.
-outputting the spanning read info: /tmp/nxf.0HSd2SUmKP/fi_workdir/tih_rna_sample_00089_23H5VFLT4_s39.star.cSorted.dupsMarked.bam.fusion_spanning_info.
 - counting read alignments among fusion contigs.

[1000]   -fusion SPANNING read extraction for scaff: AC015911.9--SLFN12L

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[89000]   -fusion SPANNING read extraction for scaff: ADNP--KATNBL1

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[159000]   -fusion SPANNING read extraction for scaff: ARAP1--FCHSD2

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[48000]   -fusion SPANNING read extraction for scaff: AVEN--NFATC2

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[92000]   -fusion SPANNING read extraction for scaff: CASZ1--UBE4B

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[84000]   -fusion SPANNING read extraction for scaff: CRYZL2P--SEC16B

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[42000]   -fusion SPANNING read extraction for scaff: FAM135A--AL080275.1

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[43000]   -fusion SPANNING read extraction for scaff: FAM135A--AL365226.1

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[7000]   -fusion SPANNING read extraction for scaff: FBXO25--AC240565.1

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[83000]   -fusion SPANNING read extraction for scaff: MAPK6--TRPM7

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[143000]   -fusion SPANNING read extraction for scaff: PIP5K1B--TJP2

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[51000]   
[52000]   -fusion SPANNING read extraction for scaff: PRELID3A--AFG3L2

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[25000]   
[26000]   -fusion SPANNING read extraction for scaff: PRSS27--TPSB2

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[68000]   
[69000]   
[70000]   -fusion SPANNING read extraction for scaff: PTPRK--RSPO3

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[54000]   
[55000]   
[56000]   
[57000]   -fusion SPANNING read extraction for scaff: RAI1--DRC3

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[81000]   
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[85000]   
[86000]   
[87000]   -fusion SPANNING read extraction for scaff: ROCK1--AFG3L2

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[22000]   
[23000]   -fusion SPANNING read extraction for scaff: SAE1--AC011495.1

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[110000]   
[111000]   
[112000]   
[113000]   
[114000]   
[115000]   
[116000]   -fusion SPANNING read extraction for scaff: SF3B3--COG4

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[54000]   
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[57000]   
[58000]   
[59000]   -fusion SPANNING read extraction for scaff: SIN3A--CORO2B

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[8000]   
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[11000]   
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[13000]   
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[17000]   
[18000]   -fusion SPANNING read extraction for scaff: SPIRE1--GREB1L

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[67000]   
[68000]   
[69000]   
[70000]   
[71000]   
[72000]   
[73000]   -fusion SPANNING read extraction for scaff: SPRED1--ATP10A

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[66000]   
[67000]   -fusion SPANNING read extraction for scaff: STX16--NPEPL1

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[44000]   
[45000]   -fusion SPANNING read extraction for scaff: TAF4--UBE2Q2

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[8000]   
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[17000]   -fusion SPANNING read extraction for scaff: TLK2--AC240565.1

[1000]   
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[3000]   
[4000]   -fusion SPANNING read extraction for scaff: TLK2P1--AC110079.1

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[54000]   
[55000]   
[56000]   -fusion SPANNING read extraction for scaff: TMEM87B--MERTK

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[73000]   
[74000]   
[75000]   -fusion SPANNING read extraction for scaff: TRPM7--TMOD3

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[82000]   
[83000]   -fusion SPANNING read extraction for scaff: TRPM7--MAPK6

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[13000]   
[14000]   -fusion SPANNING read extraction for scaff: TVP23C--CDRT4

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[19000]   -fusion SPANNING read extraction for scaff: VAPB--AURKA

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[90000]   -fusion SPANNING read extraction for scaff: VWA8--ZNF346

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[81000]   
[82000]   -fusion SPANNING read extraction for scaff: WSB2--NOS1
-filtered reads reasons: $VAR1 = {
          'lacks exon overlap' => 36444
        };
EM: Starting log likelihood: -9227.192266
EM: Round [1] log likelihood: -9220.058251
EM: Round [2] log likelihood: -9220.032871
EM: Round [3] log likelihood: -9220.032021
EM: Round [4] log likelihood: -9220.031988
EM: Stopping iterations at round 4 due to insufficient improvement in likelihood.
[bam_sort_core] merging from 0 files and 8 in-memory blocks...
-extracting read coordinates from /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39.consolidated.bam into /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39.consolidated.bam.read_coords

CMD: touch /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39.consolidated.bam.read_coords.ok
CMD: /usr/bin/sort --parallel=1 -S10G -T . -k1,1 -k2,2 -k4,4n /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39.consolidated.bam.read_coords > /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39.consolidated.bam.read_coords.sort_by_readname
CMD: /usr/bin/sort --parallel=1 -S10G -T . -k1,1 -k3,3n /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39.consolidated.bam.frag_coords > /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39.consolidated.bam.frag_coords.coord_sorted
CMD: /usr/local/src/STAR-Fusion/FusionInspector/FusionFilter/util/blast_filter.pl --fusion_preds /tmp/nxf.0HSd2SUmKP/fi_workdir/tih_rna_sample_00089_23H5VFLT4_s39.fusion_preds.coalesced.summary.EMadj.min_frag_thresh.wSpliceInfo --genome_lib_dir ctat_genome_lib_build_dir
CMD: /usr/local/src/STAR-Fusion/FusionInspector/FusionFilter/util/promiscuity_filter.pl --fusion_preds /tmp/nxf.0HSd2SUmKP/fi_workdir/tih_rna_sample_00089_23H5VFLT4_s39.fusion_preds.coalesced.summary.EMadj.min_frag_thresh.wSpliceInfo.post_blast_filter  --genome_lib_dir ctat_genome_lib_build_dir  --max_promiscuity 10  --min_pct_dom_promiscuity 50 
CMD: cp /tmp/nxf.0HSd2SUmKP/fi_workdir/tih_rna_sample_00089_23H5VFLT4_s39.fusion_preds.coalesced.summary.EMadj.min_frag_thresh.wSpliceInfo.post_blast_filter.post_promisc_filter /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39.post_blast_and_promiscuity_filter
-done, see /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39.post_blast_and_promiscuity_filter.annot_filter.pass
EM: Starting log likelihood: -8960.516585
EM: Round [1] log likelihood: -8956.183808
EM: Round [2] log likelihood: -8956.159390
EM: Round [3] log likelihood: -8956.158540
EM: Round [4] log likelihood: -8956.158507
EM: Stopping iterations at round 4 due to insufficient improvement in likelihood.
-total frags in /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39_1.fastp.fastq.gz: 296909533
Warning - not locating file: /tmp/nxf.0HSd2SUmKP/tih_rna_sample_00089_23H5VFLT4_s39.gmap_trinity_GG.fusions.gff3.bed
WARNING, no entry stored in dbm for [ENSG00000280136.2]
WARNING, no entry stored in dbm for [ENSG00000280136.2]
WARNING, no entry stored in dbm for [ENSG00000280136.2]
WARNING, no entry stored in dbm for [ENSG00000242193.11]
WARNING, no entry stored in dbm for [ENSG00000242193.11]
WARNING, no entry stored in dbm for [ENSG00000242193.11]
WARNING, no entry stored in dbm for [ENSG00000242193.11]
WARNING, no entry stored in dbm for [ENSG00000226049.3]
WARNING, no entry stored in dbm for [ENSG00000260404.3]
WARNING, no entry stored in dbm for [ENSG00000286030.2]
WARNING, no entry stored in dbm for [ENSG00000286030.2]
WARNING, no entry stored in dbm for [ENSG00000286065.2]
ls: cannot access 'IGV_inputs': No such file or directory