Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/e0/f09fed2a84222b143b2e964fb3db64/tih_rna_sample_00420_23H5VFLT4_s45.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fa/2f6294ab9f2b78844617cda670c13a/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/fa/2f6294ab9f2b78844617cda670c13a/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5b456d70-fab3-4fcc-916c-bc437f411fba/48/d36e0303d259ad82d7d96e756f6134/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 3 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 60
Pass (FILTER=PASS): 11 (18.3%)
Fail (FILTER=FAIL): 49 (81.7%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 3
All 3 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 5
confidence_below_min(medium<high): 5
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 3
confidence_below_min(medium<high);aih_curated_blacklist: 2
confidence_below_min(low<high): 2
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(2.0<8.0);aih_curated_blacklist: 1
Breakdown by confidence:
high: 11 pass, 0 fail (total: 11)
low: 0 pass, 26 fail (total: 26)
medium: 0 pass, 23 fail (total: 23)
Arriba filter: 60 rows -> 11 PASS; wrote tih_rna_sample_00420_23H5VFLT4_s45.arriba.fusions.filtered.tsv and tih_rna_sample_00420_23H5VFLT4_s45.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00420_23H5VFLT4_s45.arriba.fusions.filter_summary.txt