Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/2b/57e00b706f3152a392698bb9b65795/tih_rna_sample_00425_23H5VFLT4_s46.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/55/098948f03ac69e9857921d4d92e9c6/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/55/098948f03ac69e9857921d4d92e9c6/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-5b456d70-fab3-4fcc-916c-bc437f411fba/48/d36e0303d259ad82d7d96e756f6134/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 5 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 90
  Pass (FILTER=PASS): 5 (5.6%)
  Fail (FILTER=FAIL): 85 (94.4%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 5
  All 5 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 24
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 15
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 12
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 9
  confidence_below_min(low<high): 5
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 3
  confidence_below_min(medium<high);aih_curated_blacklist: 3
  confidence_below_min(medium<high): 3
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 2
  total_reads_below_min(3.0<8.0): 2
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 2
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 1
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 1
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0);aih_curated_blacklist: 1
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0);aih_curated_blacklist: 1

Breakdown by confidence:
  high: 5 pass, 2 fail (total: 7)
  low: 0 pass, 38 fail (total: 38)
  medium: 0 pass, 45 fail (total: 45)
Arriba filter: 90 rows -> 5 PASS; wrote tih_rna_sample_00425_23H5VFLT4_s46.arriba.fusions.filtered.tsv and tih_rna_sample_00425_23H5VFLT4_s46.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00425_23H5VFLT4_s46.arriba.fusions.filter_summary.txt