Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/cd/41b3525c83bb5d406b10fb1fc905fb/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a0/8d93d025990bd719b738d11f225692/KG1_FFPE_01_RNA_0003_B23LG7FLT4_2.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/cd/41b3525c83bb5d406b10fb1fc905fb/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-6ef41cd9-2e18-4687-842c-3f6f49c5643f/f2/edcdb43d4676ed2a5254ed1bf31faa/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 7 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 187
Pass (FILTER=PASS): 27 (14.4%)
Fail (FILTER=FAIL): 160 (85.6%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 7
All 7 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 29
confidence_below_min(medium<high): 24
confidence_below_min(low<high): 17
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 9
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 9
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
Breakdown by confidence:
high: 27 pass, 2 fail (total: 29)
low: 0 pass, 96 fail (total: 96)
medium: 0 pass, 62 fail (total: 62)
Arriba filter: 187 rows -> 27 PASS; wrote KG1_FFPE_01_RNA_0003_B23LG7FLT4_2.arriba.fusions.filtered.tsv and KG1_FFPE_01_RNA_0003_B23LG7FLT4_2.arriba.fusions.filtered_pass_only.tsv
Summary written to: KG1_FFPE_01_RNA_0003_B23LG7FLT4_2.arriba.fusions.filter_summary.txt