File Info

Filename
.command.log
Full Path
s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d3/2e5fcef5a1fc656a73a83da6692805/.command.log
Size
17.8 KB
Attempt
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/ensembl/ctat_ref_annot.interval_list
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/2c/3f5ec9f0a169d4d484b81b4e99fa4e/BreastNP_FFPE_L04_RNA_01_B23LG7FLT4_1.Aligned.sortedByCoord.out.bam.bai
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d3/2e5fcef5a1fc656a73a83da6692805/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d3/2e5fcef5a1fc656a73a83da6692805/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/ensembl/ref_annot.gtf.refflat
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/79/71117a58f0b32aa82ed8ea882f6136/BreastNP_FFPE_L04_RNA_01_B23LG7FLT4_1.Aligned.sortedByCoord.out.bam
==> STAGING COMPLETE (6 inputs)

/usr/local/bin/picard: line 5: warning: setlocale: LC_ALL: cannot change locale (en_US.UTF-8): No such file or directory
May 28, 2026 8:15:02 PM com.intel.gkl.NativeLibraryLoader load
INFO: Loading libgkl_compression.so from jar:file:/usr/local/share/picard-3.1.0-0/picard.jar!/com/intel/gkl/native/libgkl_compression.so
[Thu May 28 20:15:02 GMT 2026] CollectRnaSeqMetrics --REF_FLAT ref_annot.gtf.refflat --RIBOSOMAL_INTERVALS ctat_ref_annot.interval_list --STRAND_SPECIFICITY NONE --INPUT BreastNP_FFPE_L04_RNA_01_B23LG7FLT4_1.Aligned.sortedByCoord.out.bam --OUTPUT BreastNP_FFPE_L04_RNA_01_B23LG7FLT4_1_rna_metrics.txt --TMP_DIR ./tmp --MINIMUM_LENGTH 500 --RRNA_FRAGMENT_PERCENTAGE 0.8 --METRIC_ACCUMULATION_LEVEL ALL_READS --END_BIAS_BASES 100 --ASSUME_SORTED true --STOP_AFTER 0 --VERBOSITY INFO --QUIET false --VALIDATION_STRINGENCY STRICT --COMPRESSION_LEVEL 5 --MAX_RECORDS_IN_RAM 500000 --CREATE_INDEX false --CREATE_MD5_FILE false --help false --version false --showHidden false --USE_JDK_DEFLATER false --USE_JDK_INFLATER false
[Thu May 28 20:15:02 GMT 2026] Executing as ?@nf-d32e5fcef5a1fc656a73a83da6692805-f0e96-ztzr6 on Linux 6.12.83 amd64; OpenJDK 64-Bit Server VM 20-internal-adhoc..src; Deflater: Intel; Inflater: Intel; Provider GCS is available; Picard version: Version:3.1.0
WARNING: BAM index file /tmp/nxf.XXXXIQtj7R/BreastNP_FFPE_L04_RNA_01_B23LG7FLT4_1.Aligned.sortedByCoord.out.bam.bai is older than BAM /tmp/nxf.XXXXIQtj7R/BreastNP_FFPE_L04_RNA_01_B23LG7FLT4_1.Aligned.sortedByCoord.out.bam
INFO	2026-05-28 20:15:05	CollectRnaSeqMetrics	Loaded 58279 genes.
INFO	2026-05-28 20:15:17	SinglePassSamProgram	Processed     1,000,000 records.  Elapsed time: 00:00:12s.  Time for last 1,000,000:   12s.  Last read position: chr1:17,687,621
INFO	2026-05-28 20:15:29	SinglePassSamProgram	Processed     2,000,000 records.  Elapsed time: 00:00:24s.  Time for last 1,000,000:   12s.  Last read position: chr1:35,192,514
INFO	2026-05-28 20:15:44	SinglePassSamProgram	Processed     3,000,000 records.  Elapsed time: 00:00:39s.  Time for last 1,000,000:   15s.  Last read position: chr1:77,129,495
INFO	2026-05-28 20:15:52	SinglePassSamProgram	Processed     4,000,000 records.  Elapsed time: 00:00:47s.  Time for last 1,000,000:    7s.  Last read position: chr1:148,615,701
INFO	2026-05-28 20:16:07	SinglePassSamProgram	Processed     5,000,000 records.  Elapsed time: 00:01:01s.  Time for last 1,000,000:   14s.  Last read position: chr1:156,670,333
INFO	2026-05-28 20:16:18	SinglePassSamProgram	Processed     6,000,000 records.  Elapsed time: 00:01:12s.  Time for last 1,000,000:   10s.  Last read position: chr1:207,886,756
INFO	2026-05-28 20:16:33	SinglePassSamProgram	Processed     7,000,000 records.  Elapsed time: 00:01:27s.  Time for last 1,000,000:   15s.  Last read position: chr2:24,683,110
INFO	2026-05-28 20:16:39	SinglePassSamProgram	Processed     8,000,000 records.  Elapsed time: 00:01:34s.  Time for last 1,000,000:    6s.  Last read position: chr2:43,260,074
INFO	2026-05-28 20:16:51	SinglePassSamProgram	Processed     9,000,000 records.  Elapsed time: 00:01:46s.  Time for last 1,000,000:   11s.  Last read position: chr2:101,859,736
INFO	2026-05-28 20:17:04	SinglePassSamProgram	Processed    10,000,000 records.  Elapsed time: 00:01:59s.  Time for last 1,000,000:   13s.  Last read position: chr2:188,994,548
INFO	2026-05-28 20:17:21	SinglePassSamProgram	Processed    11,000,000 records.  Elapsed time: 00:02:15s.  Time for last 1,000,000:   16s.  Last read position: chr2:219,558,386
INFO	2026-05-28 20:17:36	SinglePassSamProgram	Processed    12,000,000 records.  Elapsed time: 00:02:31s.  Time for last 1,000,000:   15s.  Last read position: chr3:30,963,602
INFO	2026-05-28 20:17:49	SinglePassSamProgram	Processed    13,000,000 records.  Elapsed time: 00:02:43s.  Time for last 1,000,000:   12s.  Last read position: chr3:52,480,337
INFO	2026-05-28 20:18:00	SinglePassSamProgram	Processed    14,000,000 records.  Elapsed time: 00:02:55s.  Time for last 1,000,000:   11s.  Last read position: chr3:133,586,626
INFO	2026-05-28 20:18:13	SinglePassSamProgram	Processed    15,000,000 records.  Elapsed time: 00:03:08s.  Time for last 1,000,000:   12s.  Last read position: chr4:1,823,023
INFO	2026-05-28 20:18:25	SinglePassSamProgram	Processed    16,000,000 records.  Elapsed time: 00:03:19s.  Time for last 1,000,000:   11s.  Last read position: chr4:104,494,739
INFO	2026-05-28 20:18:40	SinglePassSamProgram	Processed    17,000,000 records.  Elapsed time: 00:03:35s.  Time for last 1,000,000:   15s.  Last read position: chr5:31,526,590
INFO	2026-05-28 20:18:52	SinglePassSamProgram	Processed    18,000,000 records.  Elapsed time: 00:03:47s.  Time for last 1,000,000:   12s.  Last read position: chr5:136,054,800
INFO	2026-05-28 20:19:01	SinglePassSamProgram	Processed    19,000,000 records.  Elapsed time: 00:03:55s.  Time for last 1,000,000:    8s.  Last read position: chr5:157,744,023
INFO	2026-05-28 20:19:20	SinglePassSamProgram	Processed    20,000,000 records.  Elapsed time: 00:04:14s.  Time for last 1,000,000:   18s.  Last read position: chr6:15,334,513
INFO	2026-05-28 20:19:35	SinglePassSamProgram	Processed    21,000,000 records.  Elapsed time: 00:04:30s.  Time for last 1,000,000:   15s.  Last read position: chr6:32,081,604
INFO	2026-05-28 20:20:00	SinglePassSamProgram	Processed    22,000,000 records.  Elapsed time: 00:04:54s.  Time for last 1,000,000:   24s.  Last read position: chr6:79,203,580
INFO	2026-05-28 20:20:14	SinglePassSamProgram	Processed    23,000,000 records.  Elapsed time: 00:05:09s.  Time for last 1,000,000:   14s.  Last read position: chr6:151,353,644
INFO	2026-05-28 20:20:36	SinglePassSamProgram	Processed    24,000,000 records.  Elapsed time: 00:05:31s.  Time for last 1,000,000:   22s.  Last read position: chr7:23,507,440
INFO	2026-05-28 20:20:52	SinglePassSamProgram	Processed    25,000,000 records.  Elapsed time: 00:05:46s.  Time for last 1,000,000:   15s.  Last read position: chr7:75,557,706
INFO	2026-05-28 20:21:11	SinglePassSamProgram	Processed    26,000,000 records.  Elapsed time: 00:06:05s.  Time for last 1,000,000:   19s.  Last read position: chr7:102,654,713
INFO	2026-05-28 20:21:22	SinglePassSamProgram	Processed    27,000,000 records.  Elapsed time: 00:06:17s.  Time for last 1,000,000:   11s.  Last read position: chr7:152,154,034
INFO	2026-05-28 20:21:39	SinglePassSamProgram	Processed    28,000,000 records.  Elapsed time: 00:06:34s.  Time for last 1,000,000:   17s.  Last read position: chr8:41,934,447
INFO	2026-05-28 20:21:56	SinglePassSamProgram	Processed    29,000,000 records.  Elapsed time: 00:06:51s.  Time for last 1,000,000:   16s.  Last read position: chr8:127,740,760
INFO	2026-05-28 20:22:06	SinglePassSamProgram	Processed    30,000,000 records.  Elapsed time: 00:07:01s.  Time for last 1,000,000:   10s.  Last read position: chr9:14,116,232
INFO	2026-05-28 20:22:17	SinglePassSamProgram	Processed    31,000,000 records.  Elapsed time: 00:07:11s.  Time for last 1,000,000:   10s.  Last read position: chr9:96,937,240
INFO	2026-05-28 20:22:33	SinglePassSamProgram	Processed    32,000,000 records.  Elapsed time: 00:07:28s.  Time for last 1,000,000:   16s.  Last read position: chr9:131,468,679
INFO	2026-05-28 20:22:45	SinglePassSamProgram	Processed    33,000,000 records.  Elapsed time: 00:07:40s.  Time for last 1,000,000:   11s.  Last read position: chr10:17,359,539
INFO	2026-05-28 20:23:04	SinglePassSamProgram	Processed    34,000,000 records.  Elapsed time: 00:07:58s.  Time for last 1,000,000:   18s.  Last read position: chr10:77,809,708
INFO	2026-05-28 20:23:15	SinglePassSamProgram	Processed    35,000,000 records.  Elapsed time: 00:08:10s.  Time for last 1,000,000:   11s.  Last read position: chr10:125,838,278
INFO	2026-05-28 20:23:26	SinglePassSamProgram	Processed    36,000,000 records.  Elapsed time: 00:08:20s.  Time for last 1,000,000:   10s.  Last read position: chr11:14,643,986
INFO	2026-05-28 20:23:40	SinglePassSamProgram	Processed    37,000,000 records.  Elapsed time: 00:08:34s.  Time for last 1,000,000:   14s.  Last read position: chr11:62,528,929
INFO	2026-05-28 20:23:57	SinglePassSamProgram	Processed    38,000,000 records.  Elapsed time: 00:08:52s.  Time for last 1,000,000:   17s.  Last read position: chr11:68,312,724
INFO	2026-05-28 20:24:18	SinglePassSamProgram	Processed    39,000,000 records.  Elapsed time: 00:09:13s.  Time for last 1,000,000:   20s.  Last read position: chr11:114,064,077
INFO	2026-05-28 20:24:38	SinglePassSamProgram	Processed    40,000,000 records.  Elapsed time: 00:09:32s.  Time for last 1,000,000:   19s.  Last read position: chr12:8,224,718
INFO	2026-05-28 20:24:49	SinglePassSamProgram	Processed    41,000,000 records.  Elapsed time: 00:09:44s.  Time for last 1,000,000:   11s.  Last read position: chr12:52,520,045
INFO	2026-05-28 20:25:14	SinglePassSamProgram	Processed    42,000,000 records.  Elapsed time: 00:10:08s.  Time for last 1,000,000:   24s.  Last read position: chr12:66,152,286
INFO	2026-05-28 20:25:33	SinglePassSamProgram	Processed    43,000,000 records.  Elapsed time: 00:10:28s.  Time for last 1,000,000:   19s.  Last read position: chr12:122,133,452
INFO	2026-05-28 20:25:50	SinglePassSamProgram	Processed    44,000,000 records.  Elapsed time: 00:10:45s.  Time for last 1,000,000:   17s.  Last read position: chr13:50,843,495
INFO	2026-05-28 20:26:12	SinglePassSamProgram	Processed    45,000,000 records.  Elapsed time: 00:11:07s.  Time for last 1,000,000:   21s.  Last read position: chr14:39,181,488
INFO	2026-05-28 20:26:33	SinglePassSamProgram	Processed    46,000,000 records.  Elapsed time: 00:11:27s.  Time for last 1,000,000:   20s.  Last read position: chr14:95,260,818
INFO	2026-05-28 20:26:57	SinglePassSamProgram	Processed    47,000,000 records.  Elapsed time: 00:11:52s.  Time for last 1,000,000:   24s.  Last read position: chr15:42,746,053
INFO	2026-05-28 20:27:17	SinglePassSamProgram	Processed    48,000,000 records.  Elapsed time: 00:12:12s.  Time for last 1,000,000:   20s.  Last read position: chr15:77,467,154
INFO	2026-05-28 20:27:40	SinglePassSamProgram	Processed    49,000,000 records.  Elapsed time: 00:12:35s.  Time for last 1,000,000:   22s.  Last read position: chr16:2,093,614
INFO	2026-05-28 20:28:03	SinglePassSamProgram	Processed    50,000,000 records.  Elapsed time: 00:12:58s.  Time for last 1,000,000:   23s.  Last read position: chr16:15,127,728
INFO	2026-05-28 20:28:12	SinglePassSamProgram	Processed    51,000,000 records.  Elapsed time: 00:13:07s.  Time for last 1,000,000:    8s.  Last read position: chr16:22,523,832
INFO	2026-05-28 20:28:23	SinglePassSamProgram	Processed    52,000,000 records.  Elapsed time: 00:13:18s.  Time for last 1,000,000:   11s.  Last read position: chr16:30,729,220
INFO	2026-05-28 20:28:40	SinglePassSamProgram	Processed    53,000,000 records.  Elapsed time: 00:13:35s.  Time for last 1,000,000:   16s.  Last read position: chr16:83,161,630
INFO	2026-05-28 20:28:57	SinglePassSamProgram	Processed    54,000,000 records.  Elapsed time: 00:13:52s.  Time for last 1,000,000:   16s.  Last read position: chr17:7,384,700
INFO	2026-05-28 20:29:12	SinglePassSamProgram	Processed    55,000,000 records.  Elapsed time: 00:14:07s.  Time for last 1,000,000:   15s.  Last read position: chr17:28,701,573
INFO	2026-05-28 20:29:26	SinglePassSamProgram	Processed    56,000,000 records.  Elapsed time: 00:14:20s.  Time for last 1,000,000:   13s.  Last read position: chr17:42,300,129
INFO	2026-05-28 20:29:41	SinglePassSamProgram	Processed    57,000,000 records.  Elapsed time: 00:14:35s.  Time for last 1,000,000:   15s.  Last read position: chr17:50,187,967
INFO	2026-05-28 20:29:56	SinglePassSamProgram	Processed    58,000,000 records.  Elapsed time: 00:14:51s.  Time for last 1,000,000:   15s.  Last read position: chr17:50,194,754
INFO	2026-05-28 20:30:15	SinglePassSamProgram	Processed    59,000,000 records.  Elapsed time: 00:15:09s.  Time for last 1,000,000:   18s.  Last read position: chr17:62,573,302
INFO	2026-05-28 20:30:42	SinglePassSamProgram	Processed    60,000,000 records.  Elapsed time: 00:15:37s.  Time for last 1,000,000:   27s.  Last read position: chr17:81,512,113
INFO	2026-05-28 20:31:04	SinglePassSamProgram	Processed    61,000,000 records.  Elapsed time: 00:15:59s.  Time for last 1,000,000:   21s.  Last read position: chr18:77,017,032
INFO	2026-05-28 20:31:17	SinglePassSamProgram	Processed    62,000,000 records.  Elapsed time: 00:16:12s.  Time for last 1,000,000:   13s.  Last read position: chr19:6,709,826
INFO	2026-05-28 20:31:35	SinglePassSamProgram	Processed    63,000,000 records.  Elapsed time: 00:16:29s.  Time for last 1,000,000:   17s.  Last read position: chr19:15,244,267
INFO	2026-05-28 20:31:43	SinglePassSamProgram	Processed    64,000,000 records.  Elapsed time: 00:16:38s.  Time for last 1,000,000:    8s.  Last read position: chr19:35,269,140
INFO	2026-05-28 20:31:55	SinglePassSamProgram	Processed    65,000,000 records.  Elapsed time: 00:16:50s.  Time for last 1,000,000:   12s.  Last read position: chr19:42,287,204
INFO	2026-05-28 20:32:07	SinglePassSamProgram	Processed    66,000,000 records.  Elapsed time: 00:17:02s.  Time for last 1,000,000:   11s.  Last read position: chr19:49,490,532
INFO	2026-05-28 20:32:21	SinglePassSamProgram	Processed    67,000,000 records.  Elapsed time: 00:17:16s.  Time for last 1,000,000:   14s.  Last read position: chr20:2,484,216
INFO	2026-05-28 20:32:42	SinglePassSamProgram	Processed    68,000,000 records.  Elapsed time: 00:17:37s.  Time for last 1,000,000:   20s.  Last read position: chr20:45,952,339
INFO	2026-05-28 20:32:55	SinglePassSamProgram	Processed    69,000,000 records.  Elapsed time: 00:17:49s.  Time for last 1,000,000:   12s.  Last read position: chr21:8,214,701
INFO	2026-05-28 20:32:57	SinglePassSamProgram	Processed    70,000,000 records.  Elapsed time: 00:17:51s.  Time for last 1,000,000:    2s.  Last read position: chr21:8,217,026
INFO	2026-05-28 20:32:58	SinglePassSamProgram	Processed    71,000,000 records.  Elapsed time: 00:17:53s.  Time for last 1,000,000:    1s.  Last read position: chr21:8,258,948
INFO	2026-05-28 20:33:00	SinglePassSamProgram	Processed    72,000,000 records.  Elapsed time: 00:17:55s.  Time for last 1,000,000:    1s.  Last read position: chr21:8,397,817
INFO	2026-05-28 20:33:02	SinglePassSamProgram	Processed    73,000,000 records.  Elapsed time: 00:17:57s.  Time for last 1,000,000:    2s.  Last read position: chr21:8,400,357
INFO	2026-05-28 20:33:04	SinglePassSamProgram	Processed    74,000,000 records.  Elapsed time: 00:17:59s.  Time for last 1,000,000:    1s.  Last read position: chr21:8,442,047
INFO	2026-05-28 20:33:06	SinglePassSamProgram	Processed    75,000,000 records.  Elapsed time: 00:18:01s.  Time for last 1,000,000:    1s.  Last read position: chr21:8,444,587
INFO	2026-05-28 20:33:21	SinglePassSamProgram	Processed    76,000,000 records.  Elapsed time: 00:18:16s.  Time for last 1,000,000:   15s.  Last read position: chr21:46,124,658
INFO	2026-05-28 20:33:36	SinglePassSamProgram	Processed    77,000,000 records.  Elapsed time: 00:18:31s.  Time for last 1,000,000:   15s.  Last read position: chr22:37,312,105
INFO	2026-05-28 20:33:51	SinglePassSamProgram	Processed    78,000,000 records.  Elapsed time: 00:18:45s.  Time for last 1,000,000:   14s.  Last read position: chrX:2,726,309
INFO	2026-05-28 20:34:07	SinglePassSamProgram	Processed    79,000,000 records.  Elapsed time: 00:19:02s.  Time for last 1,000,000:   16s.  Last read position: chrX:101,391,503
INFO	2026-05-28 20:34:22	SinglePassSamProgram	Processed    80,000,000 records.  Elapsed time: 00:19:16s.  Time for last 1,000,000:   14s.  Last read position: GL000220.1:114,119
INFO	2026-05-28 20:34:23	SinglePassSamProgram	Processed    81,000,000 records.  Elapsed time: 00:19:18s.  Time for last 1,000,000:    1s.  Last read position: GL000220.1:115,558
INFO	2026-05-28 20:34:24	SinglePassSamProgram	Processed    82,000,000 records.  Elapsed time: 00:19:19s.  Time for last 1,000,000:    1s.  Last read position: GL000220.1:157,871
INFO	2026-05-28 20:34:26	SinglePassSamProgram	Processed    83,000,000 records.  Elapsed time: 00:19:21s.  Time for last 1,000,000:    1s.  Last read position: GL000220.1:159,525
INFO	2026-05-28 20:34:27	SinglePassSamProgram	Processed    84,000,000 records.  Elapsed time: 00:19:22s.  Time for last 1,000,000:    1s.  Last read position: KI270733.1:129,665
INFO	2026-05-28 20:34:29	SinglePassSamProgram	Processed    85,000,000 records.  Elapsed time: 00:19:24s.  Time for last 1,000,000:    1s.  Last read position: KI270733.1:132,403
INFO	2026-05-28 20:34:30	SinglePassSamProgram	Processed    86,000,000 records.  Elapsed time: 00:19:25s.  Time for last 1,000,000:    1s.  Last read position: KI270733.1:171,711
INFO	2026-05-28 20:34:32	SinglePassSamProgram	Processed    87,000,000 records.  Elapsed time: 00:19:27s.  Time for last 1,000,000:    1s.  Last read position: KI270733.1:176,713
INFO	2026-05-28 20:34:33	SinglePassSamProgram	Processed    88,000,000 records.  Elapsed time: 00:19:28s.  Time for last 1,000,000:    1s.  Last read position: KI270733.1:179,526
INFO	2026-05-28 20:34:35	SinglePassSamProgram	Processed    89,000,000 records.  Elapsed time: 00:19:30s.  Time for last 1,000,000:    1s.  Last read position: */*
[Thu May 28 20:34:37 GMT 2026] picard.analysis.CollectRnaSeqMetrics done. Elapsed time: 19.59 minutes.
Runtime.totalMemory()=2837446656