Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/de/e16245bafaac3c70293e882c4eab52/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/de/e16245bafaac3c70293e882c4eab52/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a6/3f0352bf9804fea8797d876bca4350/OvarianND_FFPE_L02_RNA_01_B23LG7FLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-f79a17a0-988d-46c3-a0fc-cc7f26b06d9c/2f/783d5e3fc4bb0e4fc378bb3e8b5e61/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 10 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 190
  Pass (FILTER=PASS): 38 (20.0%)
  Fail (FILTER=FAIL): 152 (80.0%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 10
  All 10 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 44
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 28
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 14
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 11
  confidence_below_min(low<high): 9
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 7
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 6
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 5
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 4
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 4
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 4
  total_reads_below_min(3.0<8.0): 3
  confidence_below_min(medium<high);aih_curated_blacklist: 3
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0);aih_curated_blacklist: 2
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 2

Breakdown by confidence:
  high: 38 pass, 3 fail (total: 41)
  low: 0 pass, 74 fail (total: 74)
  medium: 0 pass, 75 fail (total: 75)
Arriba filter: 190 rows -> 38 PASS; wrote OvarianND_FFPE_L02_RNA_01_B23LG7FLT4_1.arriba.fusions.filtered.tsv and OvarianND_FFPE_L02_RNA_01_B23LG7FLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: OvarianND_FFPE_L02_RNA_01_B23LG7FLT4_1.arriba.fusions.filter_summary.txt