Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f8/2b0fa589587fd1c4bb38e7f6739fcd/BVT_FFPE_TRNA_crv_04_A23WKFTLT4_2.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/34/6aff34dcfdadbadc375e8b27fda446/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/34/6aff34dcfdadbadc375e8b27fda446/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-13dfb8f7-c999-4ef0-9260-22ba79cf647d/75/c52a23060671398a8253a658f32ecc/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 6 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 83
  Pass (FILTER=PASS): 2 (2.4%)
  Fail (FILTER=FAIL): 81 (97.6%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 6
  All 6 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 19
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 12
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 7
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 7
  confidence_below_min(low<high): 6
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 6
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
  confidence_below_min(medium<high);aih_curated_blacklist: 3
  confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 3
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 2
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 2
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 2
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 2
  aih_curated_blacklist: 1

Breakdown by confidence:
  high: 2 pass, 2 fail (total: 4)
  low: 0 pass, 51 fail (total: 51)
  medium: 0 pass, 28 fail (total: 28)
Arriba filter: 83 rows -> 2 PASS; wrote BVT_FFPE_TRNA_crv_04_A23WKFTLT4_2.arriba.fusions.filtered.tsv and BVT_FFPE_TRNA_crv_04_A23WKFTLT4_2.arriba.fusions.filtered_pass_only.tsv
Summary written to: BVT_FFPE_TRNA_crv_04_A23WKFTLT4_2.arriba.fusions.filter_summary.txt