Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/5e/165fbb31a9bd37152379c778e4002f/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/5e/165fbb31a9bd37152379c778e4002f/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/73/1941706c7f1304bca4ddff949b8eb8/659_rd-T1-TRNA-1_A23MVY2LT4_2.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-bba2394f-ea06-4038-829e-f0bb41c45b0f/84/e510984b93930338ae941c5c84bcbe/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 9 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 284
Pass (FILTER=PASS): 38 (13.4%)
Fail (FILTER=FAIL): 246 (86.6%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 9
All 9 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 70
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 40
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 23
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 20
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 14
confidence_below_min(low<high): 14
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 13
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 4
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 3
Breakdown by confidence:
high: 38 pass, 5 fail (total: 43)
low: 0 pass, 125 fail (total: 125)
medium: 0 pass, 116 fail (total: 116)
Arriba filter: 284 rows -> 38 PASS; wrote 659_rd-T1-TRNA-1_A23MVY2LT4_2.arriba.fusions.filtered.tsv and 659_rd-T1-TRNA-1_A23MVY2LT4_2.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_rd-T1-TRNA-1_A23MVY2LT4_2.arriba.fusions.filter_summary.txt