Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f0/3875797284bf9bbdeb1a1ca265998b/659_cIX-T1-TRNA-1_A23MVY2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ec/263dbcb6ed7d6a9c44306f87d1da78/.command.sh
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ec/263dbcb6ed7d6a9c44306f87d1da78/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-bba2394f-ea06-4038-829e-f0bb41c45b0f/84/e510984b93930338ae941c5c84bcbe/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 8 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 271
Pass (FILTER=PASS): 36 (13.3%)
Fail (FILTER=FAIL): 235 (86.7%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 8
All 8 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 90
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 23
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 14
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 12
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 12
confidence_below_min(low<high): 11
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 10
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 2
Breakdown by confidence:
high: 36 pass, 3 fail (total: 39)
low: 0 pass, 89 fail (total: 89)
medium: 0 pass, 143 fail (total: 143)
Arriba filter: 271 rows -> 36 PASS; wrote 659_cIX-T1-TRNA-1_A23MVY2LT4_1.arriba.fusions.filtered.tsv and 659_cIX-T1-TRNA-1_A23MVY2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_cIX-T1-TRNA-1_A23MVY2LT4_1.arriba.fusions.filter_summary.txt