Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/98/4e7266c9fbea396abdc93351b09857/659_bUW-T1-TRNA-1_A23MVY2LT4_2.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f0/cc5febd4f0058de390ca0f14fdc33c/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f0/cc5febd4f0058de390ca0f14fdc33c/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-bba2394f-ea06-4038-829e-f0bb41c45b0f/84/e510984b93930338ae941c5c84bcbe/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 9 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 218
  Pass (FILTER=PASS): 10 (4.6%)
  Fail (FILTER=FAIL): 208 (95.4%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 9
  All 9 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 38
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 36
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 33
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 26
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 13
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 11
  confidence_below_min(low<high): 10
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 8
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 6
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 5
  confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 3
  confidence_below_min(medium<high);aih_curated_blacklist: 3
  total_reads_below_min(4.0<8.0): 2
  total_reads_below_min(5.0<8.0): 2
  total_reads_below_min(3.0<8.0): 2

Breakdown by confidence:
  high: 10 pass, 8 fail (total: 18)
  low: 0 pass, 112 fail (total: 112)
  medium: 0 pass, 88 fail (total: 88)
Arriba filter: 218 rows -> 10 PASS; wrote 659_bUW-T1-TRNA-1_A23MVY2LT4_2.arriba.fusions.filtered.tsv and 659_bUW-T1-TRNA-1_A23MVY2LT4_2.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_bUW-T1-TRNA-1_A23MVY2LT4_2.arriba.fusions.filter_summary.txt