Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/6c/e46e1516d98c89f05bbb3a03b86af0/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b2/17c4d8031063c86c696be83f49b13a/659_cWx-T1-TRNA-1_A23MVY2LT4_2.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/6c/e46e1516d98c89f05bbb3a03b86af0/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-bba2394f-ea06-4038-829e-f0bb41c45b0f/84/e510984b93930338ae941c5c84bcbe/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 8 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 149
Pass (FILTER=PASS): 5 (3.4%)
Fail (FILTER=FAIL): 144 (96.6%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 8
All 8 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 37
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 17
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 17
confidence_below_min(medium<high): 14
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 9
confidence_below_min(low<high): 8
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 7
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(0.0<8.0);aih_curated_blacklist: 2
total_reads_below_min(7.0<8.0): 1
total_reads_below_min(5.0<8.0): 1
Breakdown by confidence:
high: 5 pass, 5 fail (total: 10)
low: 0 pass, 111 fail (total: 111)
medium: 0 pass, 28 fail (total: 28)
Arriba filter: 149 rows -> 5 PASS; wrote 659_cWx-T1-TRNA-1_A23MVY2LT4_2.arriba.fusions.filtered.tsv and 659_cWx-T1-TRNA-1_A23MVY2LT4_2.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_cWx-T1-TRNA-1_A23MVY2LT4_2.arriba.fusions.filter_summary.txt