Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/72/6e2176ecc982911907cb2c44337381/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/72/6e2176ecc982911907cb2c44337381/.command.sh
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f7/209da1d064fe41bd22e7a2349339b6/PX_FFPE_pst_TRNA_nat_02_A23MVY2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-bba2394f-ea06-4038-829e-f0bb41c45b0f/84/e510984b93930338ae941c5c84bcbe/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 7 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 133
Pass (FILTER=PASS): 5 (3.8%)
Fail (FILTER=FAIL): 128 (96.2%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 7
All 7 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 75
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 2
aih_curated_blacklist: 1
total_reads_below_min(3.0<8.0);aih_curated_blacklist: 1
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 1
confidence_below_min(low<high);aih_curated_blacklist: 1
Breakdown by confidence:
high: 5 pass, 2 fail (total: 7)
low: 0 pass, 43 fail (total: 43)
medium: 0 pass, 83 fail (total: 83)
Arriba filter: 133 rows -> 5 PASS; wrote PX_FFPE_pst_TRNA_nat_02_A23MVY2LT4_1.arriba.fusions.filtered.tsv and PX_FFPE_pst_TRNA_nat_02_A23MVY2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: PX_FFPE_pst_TRNA_nat_02_A23MVY2LT4_1.arriba.fusions.filter_summary.txt