Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/88/e363d6339c70a78e69688ab7a1be14/PX_FFPE_gb_TRNA_nat_01_A23MVY2LT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b5/6e5b07314aaa4d40e0faa3bee452ec/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b5/6e5b07314aaa4d40e0faa3bee452ec/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-bba2394f-ea06-4038-829e-f0bb41c45b0f/84/e510984b93930338ae941c5c84bcbe/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 169
  Pass (FILTER=PASS): 8 (4.7%)
  Fail (FILTER=FAIL): 161 (95.3%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 12
  All 12 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 86
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 15
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 10
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 9
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 8
  confidence_below_min(medium<high);aih_curated_blacklist: 5
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 3
  confidence_below_min(low<high): 3
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 3
  confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 2
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 2
  total_reads_below_min(3.0<8.0): 2
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0);aih_curated_blacklist: 2
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 2
  aih_curated_blacklist: 1

Breakdown by confidence:
  high: 8 pass, 4 fail (total: 12)
  low: 0 pass, 50 fail (total: 50)
  medium: 0 pass, 107 fail (total: 107)
Arriba filter: 169 rows -> 8 PASS; wrote PX_FFPE_gb_TRNA_nat_01_A23MVY2LT4_1.arriba.fusions.filtered.tsv and PX_FFPE_gb_TRNA_nat_01_A23MVY2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: PX_FFPE_gb_TRNA_nat_01_A23MVY2LT4_1.arriba.fusions.filter_summary.txt