Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ad/132ab34a6fadce702b54e1b813b46c/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ad/132ab34a6fadce702b54e1b813b46c/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/2f/d77fbb6a7d7f31b5a15d273cd434ec/PX_FFPE_pan_TRNA_nat_02_A23MVY2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-bba2394f-ea06-4038-829e-f0bb41c45b0f/84/e510984b93930338ae941c5c84bcbe/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 4 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 64
Pass (FILTER=PASS): 1 (1.6%)
Fail (FILTER=FAIL): 63 (98.4%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 4
All 4 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 24
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 3
confidence_below_min(low<high): 3
confidence_below_min(medium<high): 2
confidence_below_min(medium<high);aih_curated_blacklist: 2
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0);aih_curated_blacklist: 1
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 1
Breakdown by confidence:
high: 1 pass, 0 fail (total: 1)
low: 0 pass, 17 fail (total: 17)
medium: 0 pass, 46 fail (total: 46)
Arriba filter: 64 rows -> 1 PASS; wrote PX_FFPE_pan_TRNA_nat_02_A23MVY2LT4_1.arriba.fusions.filtered.tsv and PX_FFPE_pan_TRNA_nat_02_A23MVY2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: PX_FFPE_pan_TRNA_nat_02_A23MVY2LT4_1.arriba.fusions.filter_summary.txt