Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/db/804b0879ccf83a4dce647b28863a20/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/db/804b0879ccf83a4dce647b28863a20/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/07/f675621e8c40f2b822dc5b7fab1c9f/659_bGW-T1-TRNA-1_A23MVY2LT4_1.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-bba2394f-ea06-4038-829e-f0bb41c45b0f/84/e510984b93930338ae941c5c84bcbe/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 16 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 260
Pass (FILTER=PASS): 26 (10.0%)
Fail (FILTER=FAIL): 234 (90.0%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 16
All 16 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 103
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 20
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 17
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 11
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
confidence_below_min(low<high): 9
confidence_below_min(medium<high);aih_curated_blacklist: 7
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0);aih_curated_blacklist: 3
Breakdown by confidence:
high: 26 pass, 3 fail (total: 29)
low: 0 pass, 90 fail (total: 90)
medium: 0 pass, 141 fail (total: 141)
Arriba filter: 260 rows -> 26 PASS; wrote 659_bGW-T1-TRNA-1_A23MVY2LT4_1.arriba.fusions.filtered.tsv and 659_bGW-T1-TRNA-1_A23MVY2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 659_bGW-T1-TRNA-1_A23MVY2LT4_1.arriba.fusions.filter_summary.txt