Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/9a/d10e5f8b0cc796736561c4c8ab3432/PX_FFPE_stm_TRNA_nat_01_A23MVY2LT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0f/45e89eaf0f571ab50c83c440f18bda/.command.sh
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/0f/45e89eaf0f571ab50c83c440f18bda/.command.run
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-bba2394f-ea06-4038-829e-f0bb41c45b0f/84/e510984b93930338ae941c5c84bcbe/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 9 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 151
  Pass (FILTER=PASS): 2 (1.3%)
  Fail (FILTER=FAIL): 149 (98.7%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 9
  All 9 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 32
  confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 20
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 14
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 13
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 12
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 10
  confidence_below_min(low<high): 9
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 6
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 6
  confidence_below_min(medium<high);aih_curated_blacklist: 5
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 4
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 4
  total_reads_below_min(4.0<8.0): 2
  confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 2
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 2

Breakdown by confidence:
  high: 2 pass, 3 fail (total: 5)
  low: 0 pass, 68 fail (total: 68)
  medium: 0 pass, 78 fail (total: 78)
Arriba filter: 151 rows -> 2 PASS; wrote PX_FFPE_stm_TRNA_nat_01_A23MVY2LT4_1.arriba.fusions.filtered.tsv and PX_FFPE_stm_TRNA_nat_01_A23MVY2LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: PX_FFPE_stm_TRNA_nat_01_A23MVY2LT4_1.arriba.fusions.filter_summary.txt