Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ad/d9ac976a334e0536e6b08427a0f8fc/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ad/d9ac976a334e0536e6b08427a0f8fc/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/55/215e5187012627e1fa08c06373fa30/1173_CRL_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-fe242a7f-c5b9-4d3f-88fa-f3e739280d3a/0e/64006b836d7933c012afba79f66ebb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 11 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 195
Pass (FILTER=PASS): 12 (6.2%)
Fail (FILTER=FAIL): 183 (93.8%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 11
All 11 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 80
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 25
confidence_below_min(low<high): 11
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 5
confidence_below_min(medium<high);aih_curated_blacklist: 5
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 2
aih_curated_blacklist: 2
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 2
Breakdown by confidence:
high: 12 pass, 4 fail (total: 16)
low: 0 pass, 83 fail (total: 83)
medium: 0 pass, 96 fail (total: 96)
Arriba filter: 195 rows -> 12 PASS; wrote 1173_CRL_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filtered.tsv and 1173_CRL_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 1173_CRL_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filter_summary.txt