Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/82/829b59a82e66b2b8430b2ff1e54853/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/82/829b59a82e66b2b8430b2ff1e54853/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/34/970bdb0ca5236e9ea0ba69c717f6c4/1173_QJL_T1_RNA_SLD_01_A23T55JLT4_2.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-fe242a7f-c5b9-4d3f-88fa-f3e739280d3a/0e/64006b836d7933c012afba79f66ebb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 4 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 309
Pass (FILTER=PASS): 69 (22.3%)
Fail (FILTER=FAIL): 240 (77.7%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 4
All 4 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 99
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 30
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 17
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 14
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 14
confidence_below_min(low<high): 12
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 10
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 8
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 7
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 2
Breakdown by confidence:
high: 69 pass, 6 fail (total: 75)
low: 0 pass, 77 fail (total: 77)
medium: 0 pass, 157 fail (total: 157)
Arriba filter: 309 rows -> 69 PASS; wrote 1173_QJL_T1_RNA_SLD_01_A23T55JLT4_2.arriba.fusions.filtered.tsv and 1173_QJL_T1_RNA_SLD_01_A23T55JLT4_2.arriba.fusions.filtered_pass_only.tsv
Summary written to: 1173_QJL_T1_RNA_SLD_01_A23T55JLT4_2.arriba.fusions.filter_summary.txt