Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/5f/03ce33e801a3095bc84207da4aa493/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/5f/03ce33e801a3095bc84207da4aa493/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/09/a638bb5d4fb7c8446d2fa41a98abfc/1173_CH0_T1_RNA_SLD_01_A23T55JLT4_2.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-fe242a7f-c5b9-4d3f-88fa-f3e739280d3a/0e/64006b836d7933c012afba79f66ebb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 7 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 117
Pass (FILTER=PASS): 10 (8.5%)
Fail (FILTER=FAIL): 107 (91.5%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 7
All 7 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 26
confidence_below_min(low<high): 14
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 11
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 5
confidence_below_min(medium<high);aih_curated_blacklist: 5
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 3
total_reads_below_min(5.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 1
Breakdown by confidence:
high: 10 pass, 2 fail (total: 12)
low: 0 pass, 39 fail (total: 39)
medium: 0 pass, 66 fail (total: 66)
Arriba filter: 117 rows -> 10 PASS; wrote 1173_CH0_T1_RNA_SLD_01_A23T55JLT4_2.arriba.fusions.filtered.tsv and 1173_CH0_T1_RNA_SLD_01_A23T55JLT4_2.arriba.fusions.filtered_pass_only.tsv
Summary written to: 1173_CH0_T1_RNA_SLD_01_A23T55JLT4_2.arriba.fusions.filter_summary.txt