Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f8/de24b4d87b366dfd607214f165f16a/1173_NFO_T1_RNA_SLD_01_A23T55JLT4_2.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ce/cdc052d8aa1ae19895288db179394b/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ce/cdc052d8aa1ae19895288db179394b/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-fe242a7f-c5b9-4d3f-88fa-f3e739280d3a/0e/64006b836d7933c012afba79f66ebb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 5 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 92
Pass (FILTER=PASS): 13 (14.1%)
Fail (FILTER=FAIL): 79 (85.9%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 5
All 5 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 19
confidence_below_min(low<high): 18
confidence_below_min(medium<high): 8
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 3
confidence_below_min(medium<high);aih_curated_blacklist: 2
confidence_below_min(low<high);aih_curated_blacklist: 2
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 1
Breakdown by confidence:
high: 13 pass, 0 fail (total: 13)
low: 0 pass, 58 fail (total: 58)
medium: 0 pass, 21 fail (total: 21)
Arriba filter: 92 rows -> 13 PASS; wrote 1173_NFO_T1_RNA_SLD_01_A23T55JLT4_2.arriba.fusions.filtered.tsv and 1173_NFO_T1_RNA_SLD_01_A23T55JLT4_2.arriba.fusions.filtered_pass_only.tsv
Summary written to: 1173_NFO_T1_RNA_SLD_01_A23T55JLT4_2.arriba.fusions.filter_summary.txt