Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/01/311af0394e539b9a467320131d34c1/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/01/311af0394e539b9a467320131d34c1/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/6e/13989fb596c557bf53b99d615c00fa/1173_RPX_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-fe242a7f-c5b9-4d3f-88fa-f3e739280d3a/0e/64006b836d7933c012afba79f66ebb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 7 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 165
Pass (FILTER=PASS): 15 (9.1%)
Fail (FILTER=FAIL): 150 (90.9%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 7
All 7 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 73
confidence_below_min(low<high): 12
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 8
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
Breakdown by confidence:
high: 15 pass, 0 fail (total: 15)
low: 0 pass, 47 fail (total: 47)
medium: 0 pass, 103 fail (total: 103)
Arriba filter: 165 rows -> 15 PASS; wrote 1173_RPX_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filtered.tsv and 1173_RPX_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 1173_RPX_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filter_summary.txt