Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/3a/66e4517ef05049d334cf362080de7d/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/3a/66e4517ef05049d334cf362080de7d/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d6/fa9e2b996fc6974e580b848fafc072/1173_LQD_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-fe242a7f-c5b9-4d3f-88fa-f3e739280d3a/0e/64006b836d7933c012afba79f66ebb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 8 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 227
Pass (FILTER=PASS): 16 (7.0%)
Fail (FILTER=FAIL): 211 (93.0%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 8
All 8 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 43
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 32
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 22
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 15
confidence_below_min(low<high): 13
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 11
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 10
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 8
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
Breakdown by confidence:
high: 16 pass, 5 fail (total: 21)
low: 0 pass, 98 fail (total: 98)
medium: 0 pass, 108 fail (total: 108)
Arriba filter: 227 rows -> 16 PASS; wrote 1173_LQD_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filtered.tsv and 1173_LQD_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 1173_LQD_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filter_summary.txt