Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/df/b6b61e0a9ec3b619232d87234208db/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/df/b6b61e0a9ec3b619232d87234208db/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/48/e1e272192e6b6e053ca1c13d7b0281/1173_N5V_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-fe242a7f-c5b9-4d3f-88fa-f3e739280d3a/0e/64006b836d7933c012afba79f66ebb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 8 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 253
Pass (FILTER=PASS): 44 (17.4%)
Fail (FILTER=FAIL): 209 (82.6%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 8
All 8 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 41
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 27
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 21
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 17
confidence_below_min(low<high): 16
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 15
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 7
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 3
total_reads_below_min(5.0<8.0): 2
confidence_below_min(medium<high);aih_curated_blacklist: 2
Breakdown by confidence:
high: 44 pass, 4 fail (total: 48)
low: 0 pass, 109 fail (total: 109)
medium: 0 pass, 96 fail (total: 96)
Arriba filter: 253 rows -> 44 PASS; wrote 1173_N5V_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filtered.tsv and 1173_N5V_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 1173_N5V_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filter_summary.txt