Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f4/4793e104b52f09c7397595c9f288e5/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f4/4793e104b52f09c7397595c9f288e5/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c7/2c28ac3d7a0b614ec2183a02d41512/1173_CH0_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-fe242a7f-c5b9-4d3f-88fa-f3e739280d3a/0e/64006b836d7933c012afba79f66ebb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 6 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 86
Pass (FILTER=PASS): 4 (4.7%)
Fail (FILTER=FAIL): 82 (95.3%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 6
All 6 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 18
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 13
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 10
confidence_below_min(low<high): 9
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 3
total_reads_below_min(5.0<8.0): 2
confidence_below_min(medium<high);aih_curated_blacklist: 2
confidence_below_min(low<high);aih_curated_blacklist: 2
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0);aih_curated_blacklist: 1
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 1
Breakdown by confidence:
high: 4 pass, 2 fail (total: 6)
low: 0 pass, 31 fail (total: 31)
medium: 0 pass, 49 fail (total: 49)
Arriba filter: 86 rows -> 4 PASS; wrote 1173_CH0_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filtered.tsv and 1173_CH0_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 1173_CH0_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filter_summary.txt