Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/20/6b2fde7bfb05622dd7185d19688890/1173_JLC_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d0/5c6487c467528c51aefb755faf360d/.command.sh
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d0/5c6487c467528c51aefb755faf360d/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-fe242a7f-c5b9-4d3f-88fa-f3e739280d3a/0e/64006b836d7933c012afba79f66ebb/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 10 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 265
Pass (FILTER=PASS): 32 (12.1%)
Fail (FILTER=FAIL): 233 (87.9%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 10
All 10 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 83
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 34
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 16
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 15
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 14
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 14
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 11
confidence_below_min(low<high): 6
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 4
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
Breakdown by confidence:
high: 32 pass, 4 fail (total: 36)
low: 0 pass, 86 fail (total: 86)
medium: 0 pass, 143 fail (total: 143)
Arriba filter: 265 rows -> 32 PASS; wrote 1173_JLC_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filtered.tsv and 1173_JLC_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: 1173_JLC_T1_RNA_SLD_01_A23T55JLT4_1.arriba.fusions.filter_summary.txt