Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/83/7d983afc8cf5742e3b3b42ffdf4463/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/32/04d225cd31eede747d8a0b9a506034/tih_rna_sample_00591_B23MVV7LT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/83/7d983afc8cf5742e3b3b42ffdf4463/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-7324c8a8-f474-426a-a5c9-715912777f94/d8/92d6652b0b8fcc763d0f3fff270437/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 217
  Pass (FILTER=PASS): 1 (0.5%)
  Fail (FILTER=FAIL): 216 (99.5%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 12
  All 12 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 43
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 28
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 24
  confidence_below_min(low<high): 19
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 17
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 15
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 11
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 11
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 10
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 8
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 7
  confidence_below_min(medium<high);aih_curated_blacklist: 5
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 3
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 3

Breakdown by confidence:
  high: 1 pass, 1 fail (total: 2)
  low: 0 pass, 120 fail (total: 120)
  medium: 0 pass, 95 fail (total: 95)
Arriba filter: 217 rows -> 1 PASS; wrote tih_rna_sample_00591_B23MVV7LT4_1.arriba.fusions.filtered.tsv and tih_rna_sample_00591_B23MVV7LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00591_B23MVV7LT4_1.arriba.fusions.filter_summary.txt