Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/59/93fbe5220a6f23397ad3ec29f6ad5d/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/bb/d5d9321e1dbe1708c9fecc1a7e00dd/tih_rna_sample_00583_B23MVV7LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/59/93fbe5220a6f23397ad3ec29f6ad5d/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-7324c8a8-f474-426a-a5c9-715912777f94/d8/92d6652b0b8fcc763d0f3fff270437/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 9 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 203
Pass (FILTER=PASS): 9 (4.4%)
Fail (FILTER=FAIL): 194 (95.6%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 9
All 9 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 62
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 26
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 20
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 14
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 8
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 7
confidence_below_min(low<high): 6
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 3
confidence_below_min(medium<high);aih_curated_blacklist: 3
total_reads_below_min(6.0<8.0): 2
Breakdown by confidence:
high: 9 pass, 3 fail (total: 12)
low: 0 pass, 64 fail (total: 64)
medium: 0 pass, 127 fail (total: 127)
Arriba filter: 203 rows -> 9 PASS; wrote tih_rna_sample_00583_B23MVV7LT4_1.arriba.fusions.filtered.tsv and tih_rna_sample_00583_B23MVV7LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00583_B23MVV7LT4_1.arriba.fusions.filter_summary.txt