Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/a1/3990e7a44feab6b7f4ee9f86cf57cd/tih_rna_sample_00596_B23MVV7LT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ee/734b293a0f3ad0045bdec9182798c8/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ee/734b293a0f3ad0045bdec9182798c8/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-7324c8a8-f474-426a-a5c9-715912777f94/d8/92d6652b0b8fcc763d0f3fff270437/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 13 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 332
  Pass (FILTER=PASS): 49 (14.8%)
  Fail (FILTER=FAIL): 283 (85.2%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 13
  All 13 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 73
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 41
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 30
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 19
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 17
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 15
  confidence_below_min(low<high): 14
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 9
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 8
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 8
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 7
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 6
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 6
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 4
  confidence_below_min(medium<high);aih_curated_blacklist: 4

Breakdown by confidence:
  high: 49 pass, 8 fail (total: 57)
  low: 0 pass, 122 fail (total: 122)
  medium: 0 pass, 153 fail (total: 153)
Arriba filter: 332 rows -> 49 PASS; wrote tih_rna_sample_00596_B23MVV7LT4_1.arriba.fusions.filtered.tsv and tih_rna_sample_00596_B23MVV7LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00596_B23MVV7LT4_1.arriba.fusions.filter_summary.txt