Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/6b/191a6bb4ad0a7c75d1cf39a1e72da0/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/6b/191a6bb4ad0a7c75d1cf39a1e72da0/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/93/34fbfb0d836f2e107ca20a92f163a4/tih_rna_sample_00626_B23MVV7LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-7324c8a8-f474-426a-a5c9-715912777f94/d8/92d6652b0b8fcc763d0f3fff270437/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 15 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 210
Pass (FILTER=PASS): 15 (7.1%)
Fail (FILTER=FAIL): 195 (92.9%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 15
All 15 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 80
confidence_below_min(low<high): 17
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 16
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 14
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 14
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0);aih_curated_blacklist: 3
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0);aih_curated_blacklist: 2
Breakdown by confidence:
high: 15 pass, 2 fail (total: 17)
low: 0 pass, 77 fail (total: 77)
medium: 0 pass, 116 fail (total: 116)
Arriba filter: 210 rows -> 15 PASS; wrote tih_rna_sample_00626_B23MVV7LT4_1.arriba.fusions.filtered.tsv and tih_rna_sample_00626_B23MVV7LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00626_B23MVV7LT4_1.arriba.fusions.filter_summary.txt