Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/08/24a54653ee01782dfc81e120aa5fa8/tih_rna_sample_00619_B23MVV7LT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/68/0f5cffe2e9db675f8df09d24674200/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/68/0f5cffe2e9db675f8df09d24674200/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-7324c8a8-f474-426a-a5c9-715912777f94/d8/92d6652b0b8fcc763d0f3fff270437/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 11 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 170
Pass (FILTER=PASS): 5 (2.9%)
Fail (FILTER=FAIL): 165 (97.1%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 11
All 11 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 83
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 15
confidence_below_min(low<high): 14
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 11
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 5
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 4
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0);aih_curated_blacklist: 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 1
total_reads_below_min(6.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(2.0<8.0);aih_curated_blacklist: 1
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 1
Breakdown by confidence:
high: 5 pass, 1 fail (total: 6)
low: 0 pass, 59 fail (total: 59)
medium: 0 pass, 105 fail (total: 105)
Arriba filter: 170 rows -> 5 PASS; wrote tih_rna_sample_00619_B23MVV7LT4_1.arriba.fusions.filtered.tsv and tih_rna_sample_00619_B23MVV7LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00619_B23MVV7LT4_1.arriba.fusions.filter_summary.txt