Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d2/0ecabea31277a773df45bc27672d36/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/d2/0ecabea31277a773df45bc27672d36/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/8d/f5ab7569cdca2169f998883e01b26b/tih_rna_sample_00761_B23MVV7LT4_1.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-7324c8a8-f474-426a-a5c9-715912777f94/d8/92d6652b0b8fcc763d0f3fff270437/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 2 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 52
Pass (FILTER=PASS): 7 (13.5%)
Fail (FILTER=FAIL): 45 (86.5%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 2
All 2 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 14
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 7
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 3
confidence_below_min(medium<high): 3
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 3
total_reads_below_min(4.0<8.0): 2
confidence_below_min(medium<high);aih_curated_blacklist: 2
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 2
confidence_below_min(low<high): 2
total_reads_below_min(6.0<8.0): 1
total_reads_below_min(3.0<8.0): 1
total_reads_below_min(2.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 1
Breakdown by confidence:
high: 7 pass, 5 fail (total: 12)
low: 0 pass, 26 fail (total: 26)
medium: 0 pass, 14 fail (total: 14)
Arriba filter: 52 rows -> 7 PASS; wrote tih_rna_sample_00761_B23MVV7LT4_1.arriba.fusions.filtered.tsv and tih_rna_sample_00761_B23MVV7LT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: tih_rna_sample_00761_B23MVV7LT4_1.arriba.fusions.filter_summary.txt