Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/e3/08104b335dbb3a1c355ec77f1f721c/aih-tih-sc-51d534-R1_B23WHYVLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/cf/e011d8305f631de100b9e23c6c8702/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/cf/e011d8305f631de100b9e23c6c8702/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 9 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 227
  Pass (FILTER=PASS): 22 (9.7%)
  Fail (FILTER=FAIL): 205 (90.3%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 9
  All 9 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 43
  confidence_below_min(low<high): 36
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 21
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 16
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 16
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 16
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 11
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 8
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 7
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 5
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
  confidence_below_min(medium<high);aih_curated_blacklist: 4
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 3
  aih_curated_blacklist: 2
  total_reads_below_min(3.0<8.0): 2

Breakdown by confidence:
  high: 22 pass, 6 fail (total: 28)
  low: 0 pass, 101 fail (total: 101)
  medium: 0 pass, 98 fail (total: 98)
Arriba filter: 227 rows -> 22 PASS; wrote aih-tih-sc-51d534-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-51d534-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-51d534-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt