Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/15/2615c7130eabb3e51d9a388c0ba8e6/aih-tih-sc-1ba302-R1_B23WHYVLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/23/8f38a21e0dae7bb2128d2d34908bbe/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/23/8f38a21e0dae7bb2128d2d34908bbe/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 13 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 298
  Pass (FILTER=PASS): 35 (11.7%)
  Fail (FILTER=FAIL): 263 (88.3%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 13
  All 13 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 78
  confidence_below_min(low<high): 38
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 30
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 22
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 16
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 14
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 11
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 7
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 7
  confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 6
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 5
  confidence_below_min(medium<high);aih_curated_blacklist: 4
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 4
  confidence_below_min(low<high);aih_curated_blacklist: 3
  total_reads_below_min(4.0<8.0): 3

Breakdown by confidence:
  high: 35 pass, 4 fail (total: 39)
  low: 0 pass, 129 fail (total: 129)
  medium: 0 pass, 130 fail (total: 130)
Arriba filter: 298 rows -> 35 PASS; wrote aih-tih-sc-1ba302-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-1ba302-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-1ba302-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt