Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/78/0c03ea9fd9db8624d48edefb1dc9fb/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/78/0c03ea9fd9db8624d48edefb1dc9fb/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/9c/f3d875f44b6681f23484bd2559a655/aih-tih-sc-758b5a-R1_B23WHYVLT4_1.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 7 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 280
Pass (FILTER=PASS): 21 (7.5%)
Fail (FILTER=FAIL): 259 (92.5%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 7
All 7 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 92
confidence_below_min(low<high): 27
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 26
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 20
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 18
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 15
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 7
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 7
confidence_below_min(medium<high);aih_curated_blacklist: 4
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 3
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 3
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 2
total_reads_below_min(4.0<8.0): 2
Breakdown by confidence:
high: 21 pass, 4 fail (total: 25)
low: 0 pass, 130 fail (total: 130)
medium: 0 pass, 125 fail (total: 125)
Arriba filter: 280 rows -> 21 PASS; wrote aih-tih-sc-758b5a-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-758b5a-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-758b5a-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt