Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c7/cce74c3e22e50647212b4aaca3b5f4/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c7/cce74c3e22e50647212b4aaca3b5f4/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b6/245894998169d084b1da8ab19de087/aih-tih-sc-027d27-R1_B23WHYVLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 285
Pass (FILTER=PASS): 9 (3.2%)
Fail (FILTER=FAIL): 276 (96.8%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 12
All 12 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 72
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 36
confidence_below_min(low<high): 32
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 24
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 14
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 12
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 12
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 11
confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 10
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 8
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 5
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 3
Breakdown by confidence:
high: 9 pass, 3 fail (total: 12)
low: 0 pass, 157 fail (total: 157)
medium: 0 pass, 116 fail (total: 116)
Arriba filter: 285 rows -> 9 PASS; wrote aih-tih-sc-027d27-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-027d27-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-027d27-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt