Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4f/d9b7ac85fea5cc5e44557061c04bbd/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/4f/d9b7ac85fea5cc5e44557061c04bbd/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/37/5aac74134cffc41a28410f08ed2027/aih-tih-sc-6473fb-R1_B23WHYVLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 7 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 136
Pass (FILTER=PASS): 7 (5.1%)
Fail (FILTER=FAIL): 129 (94.9%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 7
All 7 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(medium<high): 66
confidence_below_min(low<high): 19
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 7
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 5
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(5.0<8.0);aih_curated_blacklist: 1
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 1
total_reads_below_min(7.0<8.0): 1
total_reads_below_min(5.0<8.0): 1
total_reads_below_min(3.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 1
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 1
Breakdown by confidence:
high: 7 pass, 3 fail (total: 10)
low: 0 pass, 55 fail (total: 55)
medium: 0 pass, 71 fail (total: 71)
Arriba filter: 136 rows -> 7 PASS; wrote aih-tih-sc-6473fb-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-6473fb-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-6473fb-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt