Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f6/6926ccc85d78f40fe757ccbab4ece1/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/f6/6926ccc85d78f40fe757ccbab4ece1/.command.run
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/83/8439c7755ccbd11ba0d3fe3fef06e0/aih-tih-sc-c5cb90-R1_B23WHYVLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 6 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 82
Pass (FILTER=PASS): 1 (1.2%)
Fail (FILTER=FAIL): 81 (98.8%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 6
All 6 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high): 25
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 8
confidence_below_min(medium<high): 8
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 2
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 2
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 1
confidence_below_min(low<high);total_reads_below_min(7.0<8.0);aih_curated_blacklist: 1
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 1
confidence_below_min(low<high);aih_curated_blacklist: 1
Breakdown by confidence:
high: 1 pass, 0 fail (total: 1)
low: 0 pass, 65 fail (total: 65)
medium: 0 pass, 16 fail (total: 16)
Arriba filter: 82 rows -> 1 PASS; wrote aih-tih-sc-c5cb90-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-c5cb90-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-c5cb90-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt