Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b5/59ba11aee0ec19a68c198b0bc90ee5/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b5/59ba11aee0ec19a68c198b0bc90ee5/.command.sh
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/3f/952bd0cf9142e2d2fada0dcd761992/aih-tih-sc-7c610c-R1_B23WHYVLT4_1.arriba.fusions.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 10 fusion rows (breakpoint_ID in qualified set)
================================================================================
ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 154
Pass (FILTER=PASS): 17 (11.0%)
Fail (FILTER=FAIL): 137 (89.0%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 10
All 10 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high): 27
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 18
confidence_below_min(medium<high): 17
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 17
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 15
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 8
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 6
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 3
confidence_below_min(medium<high);aih_curated_blacklist: 3
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 3
confidence_below_min(low<high);aih_curated_blacklist: 3
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 2
confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 1
Breakdown by confidence:
high: 17 pass, 3 fail (total: 20)
low: 0 pass, 76 fail (total: 76)
medium: 0 pass, 58 fail (total: 58)
Arriba filter: 154 rows -> 17 PASS; wrote aih-tih-sc-7c610c-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-7c610c-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-7c610c-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt