Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/9d/933f62a9c280976dcc5a4efea26200/aih-tih-sc-97c26d-R1_B23WHYVLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c4/226f9ec1dd9c25f2542284136b0449/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c4/226f9ec1dd9c25f2542284136b0449/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 2 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 112
  Pass (FILTER=PASS): 11 (9.8%)
  Fail (FILTER=FAIL): 101 (90.2%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 2
  All 2 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 15
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 12
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 12
  confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 11
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 10
  confidence_below_min(low<high): 9
  confidence_below_min(medium<high): 8
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 4
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 3
  total_reads_below_min(3.0<8.0): 2
  confidence_below_min(medium<high);aih_curated_blacklist: 2
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 2
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 2
  total_reads_below_min(6.0<8.0): 1

Breakdown by confidence:
  high: 11 pass, 4 fail (total: 15)
  low: 0 pass, 36 fail (total: 36)
  medium: 0 pass, 61 fail (total: 61)
Arriba filter: 112 rows -> 11 PASS; wrote aih-tih-sc-97c26d-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-97c26d-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-97c26d-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt