Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/c9/7629dbc24d1965ff4ea981b92ecb16/aih-tih-sc-20b7e4-R1_B23WHYVLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b2/206133b1bb0152a86581b62a0f79cb/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/b2/206133b1bb0152a86581b62a0f79cb/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 3 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 95
  Pass (FILTER=PASS): 15 (15.8%)
  Fail (FILTER=FAIL): 80 (84.2%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 3
  All 3 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 13
  confidence_below_min(low<high): 12
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 11
  confidence_below_min(medium<high): 9
  total_reads_below_min(4.0<8.0): 5
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 5
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 3
  confidence_below_min(medium<high);aih_curated_blacklist: 3
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 3
  total_reads_below_min(7.0<8.0): 2
  total_reads_below_min(5.0<8.0): 2
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 2
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 2
  total_reads_below_min(3.0<8.0): 1

Breakdown by confidence:
  high: 15 pass, 10 fail (total: 25)
  low: 0 pass, 47 fail (total: 47)
  medium: 0 pass, 23 fail (total: 23)
Arriba filter: 95 rows -> 15 PASS; wrote aih-tih-sc-20b7e4-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-20b7e4-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-20b7e4-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt