Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/04/9df4d5d9a52e0d68857c278ca0b53e/aih-tih-sc-910896-R1_B23WHYVLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/28/6eac418adca6056d20e94eb9ece550/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/28/6eac418adca6056d20e94eb9ece550/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 8 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 174
  Pass (FILTER=PASS): 9 (5.2%)
  Fail (FILTER=FAIL): 165 (94.8%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 8
  All 8 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 28
  confidence_below_min(low<high): 27
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 19
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 18
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 11
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 11
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 10
  confidence_below_min(medium<high): 9
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 7
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 4
  confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 4
  confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 3
  confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 2
  confidence_below_min(medium<high);aih_curated_blacklist: 2
  confidence_below_min(low<high);aih_curated_blacklist: 2

Breakdown by confidence:
  high: 9 pass, 2 fail (total: 11)
  low: 0 pass, 97 fail (total: 97)
  medium: 0 pass, 66 fail (total: 66)
Arriba filter: 174 rows -> 9 PASS; wrote aih-tih-sc-910896-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-910896-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-910896-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt