Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/66/f2a40b79de01833701d66055e59760/aih-tih-sc-1d89ab-R1_B23WHYVLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/2d/f5b533c1fe31fcffb9e388d883ebdf/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/2d/f5b533c1fe31fcffb9e388d883ebdf/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 405
  Pass (FILTER=PASS): 57 (14.1%)
  Fail (FILTER=FAIL): 348 (85.9%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 12
  All 12 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 75
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 48
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 34
  confidence_below_min(low<high): 26
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 25
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 24
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 23
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 18
  confidence_below_min(medium<high);total_reads_below_min(6.0<8.0): 13
  confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 10
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 9
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 7
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 5
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 4
  confidence_below_min(medium<high);aih_curated_blacklist: 4

Breakdown by confidence:
  high: 57 pass, 13 fail (total: 70)
  low: 0 pass, 140 fail (total: 140)
  medium: 0 pass, 195 fail (total: 195)
Arriba filter: 405 rows -> 57 PASS; wrote aih-tih-sc-1d89ab-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-1d89ab-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-1d89ab-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt