Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/dd/392ffa718b72327e028a9252edb0c3/aih-tih-sc-a3a521-R1_B23WHYVLT4_1.arriba.fusions.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ed/87a44f272aeff97556da63c709a434/.command.sh
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/ed/87a44f272aeff97556da63c709a434/.command.run
  Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
  Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)

  AIH curated blacklist: matched 12 fusion rows (breakpoint_ID in qualified set)

================================================================================
ARRIBA FILTERING SUMMARY
================================================================================

Total fusions: 387
  Pass (FILTER=PASS): 36 (9.3%)
  Fail (FILTER=FAIL): 351 (90.7%)

AIH curated blacklist (blacklisted flag):
  Total blacklisted: 12
  All 12 blacklisted rows have FILTER=FAIL

Failure reasons (top 15):
  confidence_below_min(medium<high): 91
  confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 45
  confidence_below_min(low<high): 40
  confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 29
  confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 24
  confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 22
  confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 18
  confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 15
  confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 13
  confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 12
  confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 11
  confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 5
  confidence_below_min(medium<high);total_reads_below_min(7.0<8.0): 5
  confidence_below_min(low<high);aih_curated_blacklist: 3
  confidence_below_min(medium<high);aih_curated_blacklist: 2

Breakdown by confidence:
  high: 36 pass, 6 fail (total: 42)
  low: 0 pass, 164 fail (total: 164)
  medium: 0 pass, 181 fail (total: 181)
Arriba filter: 387 rows -> 36 PASS; wrote aih-tih-sc-a3a521-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-a3a521-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-a3a521-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt