Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/96/837a60f742e0e25e62776cffda5611/.command.sh
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/96/837a60f742e0e25e62776cffda5611/.command.run
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/03/91ac67a55c3b8caf1f8f6b283a2170/aih-tih-sc-7c6c07-R1_B23WHYVLT4_1.arriba.fusions.tsv
Downloading: s3://natera-platform-sandbox/pipeline-resources/AIH/rna/GRCh38/blacklist_breakpoint_database_2026-04-27.tsv
Downloading: s3://natera-rnd-pltf-dev-nextflow-scratch-01/work/stage-8900cb43-4dca-49ac-a290-1d176a2e0012/49/8453bafeca2d0250d89cdefd7ba73e/arriba_filter_config.yaml
==> STAGING COMPLETE (5 inputs)
AIH curated blacklist: matched 8 fusion rows (breakpoint_ID in qualified set)
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ARRIBA FILTERING SUMMARY
================================================================================
Total fusions: 334
Pass (FILTER=PASS): 20 (6.0%)
Fail (FILTER=FAIL): 314 (94.0%)
AIH curated blacklist (blacklisted flag):
Total blacklisted: 8
All 8 blacklisted rows have FILTER=FAIL
Failure reasons (top 15):
confidence_below_min(low<high);total_reads_below_min(1.0<8.0): 57
confidence_below_min(low<high): 54
confidence_below_min(medium<high): 36
confidence_below_min(low<high);total_reads_below_min(3.0<8.0): 30
confidence_below_min(low<high);total_reads_below_min(2.0<8.0): 30
confidence_below_min(medium<high);total_reads_below_min(3.0<8.0): 22
confidence_below_min(low<high);total_reads_below_min(4.0<8.0): 17
confidence_below_min(medium<high);total_reads_below_min(5.0<8.0): 13
confidence_below_min(low<high);total_reads_below_min(5.0<8.0): 11
confidence_below_min(low<high);total_reads_below_min(0.0<8.0): 10
confidence_below_min(medium<high);total_reads_below_min(4.0<8.0): 9
confidence_below_min(low<high);total_reads_below_min(7.0<8.0): 6
confidence_below_min(medium<high);total_reads_below_min(2.0<8.0): 4
confidence_below_min(low<high);total_reads_below_min(6.0<8.0): 4
confidence_below_min(medium<high);aih_curated_blacklist: 3
Breakdown by confidence:
high: 20 pass, 3 fail (total: 23)
low: 0 pass, 222 fail (total: 222)
medium: 0 pass, 89 fail (total: 89)
Arriba filter: 334 rows -> 20 PASS; wrote aih-tih-sc-7c6c07-R1_B23WHYVLT4_1.arriba.fusions.filtered.tsv and aih-tih-sc-7c6c07-R1_B23WHYVLT4_1.arriba.fusions.filtered_pass_only.tsv
Summary written to: aih-tih-sc-7c6c07-R1_B23WHYVLT4_1.arriba.fusions.filter_summary.txt